北京索萊寶科技
專注于生物學試劑及試劑盒領域
服務熱線：18101056239
專注于生物學試劑及試劑盒領域
服務熱線：18101056239
產品型號：K106513P
更新時間：2022-08-15
廠商性質：生產廠家
訪 問 量 ：961
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產品分類
Anti-VCAM-1 Polyclonal Antibody
| 英文名稱 | Anti-VCAM-1 Polyclonal Antibody |
|---|---|
| 宿主 | Rabbit |
| 別名 | INCAM-100;CD106;CUL 5;Cullin5;CUL5_HUMAN |
| 應用 | WB IHC |
| 稀釋比例 | WB 1:2000-5000.IHC 1:50-200. |
| 交叉反應 | Human Mouse Rat |
| 蛋白分子量 | 81kDa |
| Gene ID | 7412 |
| 保存 | Store at -20°C. Avoid freeze / thaw cycles. |
| 儲存液 | Buffer: PBS with 0.03% Proclin300, 50% glycerol, pH7.3. |
| 純化方法 | Affinity purification |
| 亞型 | IgG |
| 免疫原 | A synthetic peptide of human VCAM-1 |
| 性狀 | 液體 |
| Public Immunogen Range | A synthetic peptide of human VCAM-1 |
| Subcellular Locations | Cytoplasm Nucleus Cell membrane |
| Swiss Prot | P19320 |
| 克隆類型 | Polyclonal Antibody |
| 背景資料 | VCAM1 is important in cell-cell recognition. Appears to function in leukocyte-endothelial cell adhesion. Interacts with the integrins alpha4 beta1 (beta 1 integrin VLA4) and alpha4 beta7 on leukocytes, and mediates both adhesion and signal transduction. The VCAM1/VLA4 interaction may play a pathophysiologic role both in immune responses and in leukocyte emigration to sites of inflammation. VCAM1 is also expressed by several non endothelial cell types including some macrophages, follicular dendritic cells and bone marrow, stromal cells. |
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