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Anti-CD105 Polyclonal Antibody
產品簡介:

Anti-CD105 Polyclonal Antibody
應用 WB
稀釋比例WB 1:3000.
交叉反應Human Mouse Rat

產品型號:K106547P

更新時間:2022-08-15

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Anti-CD105 Polyclonal Antibody

英文名稱Anti-CD105 Polyclonal Antibody
宿主Rabbit
別名END;HHT1;ORW1;ENG;Endoglin
應用WB
稀釋比例WB 1:3000.
交叉反應Human Mouse Rat
蛋白分子量53kDa
Gene ID2022
保存Store at -20°C. Avoid freeze / thaw cycles.
儲存液Buffer: PBS with 0.03% Proclin300, 50% glycerol, pH7.3.
純化方法Affinity purification
亞型IgG
免疫原A synthetic peptide of human CD105
性狀液體
Public Immunogen RangeA synthetic peptide of human CD105
Subcellular LocationsMembrane Single-pass type I membrane protein
Swiss ProtP17813
克隆類型Polyclonal Antibody
背景資料This gene encodes a homodimeric transmembrane protein which is a major glycoprotein of the vascular endothelium. This protein is a component of the transforming growth factor beta receptor complex and it binds to the beta1 and beta3 peptides with high affinity. Mutations in this gene cause hereditary hemorrhagic telangiectasia, also known as Osler-Rendu-Weber syndrome 1, an autosomal dominant multisystemic vascular dysplasia. This gene may also be involved in preeclampsia and several types of cancer. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.

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