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Anti-NR3C2 Polyclonal Antibody
產(chǎn)品簡介:

Anti-NR3C2 Polyclonal Antibody
應(yīng)用 WB
稀釋比例WB 1:500-2000.
交叉反應(yīng)Human Mouse

產(chǎn)品型號(hào):K106612P

更新時(shí)間:2022-08-15

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產(chǎn)品介紹

Anti-NR3C2 Polyclonal Antibody 

英文名稱Anti-NR3C2 Polyclonal Antibody
宿主Rabbit
別名MCR;MLR;MR;NR3C2VIT
應(yīng)用WB
稀釋比例WB 1:500-2000.
交叉反應(yīng)Human Mouse
蛋白分子量107kDa
Gene ID4306
保存Store at -20°C. Avoid freeze / thaw cycles.
儲(chǔ)存液Buffer: PBS with 0.03% Proclin300, 50% glycerol, pH7.3.
純化方法Affinity purification
亞型IgG
免疫原A synthetic peptide of human NR3C2
性狀液體
Public Immunogen RangeA synthetic peptide of human NR3C2
Subcellular LocationsCytoplasm Nucleus
Swiss ProtP08235
克隆類型Polyclonal Antibody
背景資料This gene encodes the mineralocorticoid receptor, which mediates aldosterone actions on salt and water balance within restricted target cells. The protein functions as a ligand-dependent transcription factor that binds to mineralocorticoid response elements in order to transactivate target genes. Mutations in this gene cause autosomal dominant pseudohypoaldosteronism type I, a disorder characterized by urinary salt wasting. Defects in this gene are also associated with early onset hypertension with severe exacerbation in pregnancy. Alternative splicing results in multiple transcript variants.

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